{"id":56312,"date":"2025-11-06T08:25:00","date_gmt":"2025-11-06T08:25:00","guid":{"rendered":"https:\/\/manufacturing-today.com\/?p=56312"},"modified":"2025-11-05T09:35:43","modified_gmt":"2025-11-05T09:35:43","slug":"from-rna-therapies-to-smart-semiconductors-cpi-transforms-the-uks-brightest-ideas-into-market-ready-solutions","status":"publish","type":"post","link":"https:\/\/manufacturing-today.com\/news\/from-rna-therapies-to-smart-semiconductors-cpi-transforms-the-uks-brightest-ideas-into-market-ready-solutions\/","title":{"rendered":"From RNA therapies to smart semiconductors, CPI transforms the UK\u2019s brightest ideas into market-ready solutions\u00a0"},"content":{"rendered":"

As a leading independent technology innovation\u00a0center\u00a0and a founding member of the UK Government\u2019s High Value Manufacturing Catapult, CPI applies its many years of experience to maximize the potential of every great invention, giving it the best chance of becoming a successfully marketed product or process. The company acts as a catalyst bringing together academia, businesses,\u00a0government\u00a0and investors to translate bright ideas and research into\u00a0viable\u00a0solutions for the marketplace. To\u00a0facilitate\u00a0effective innovation, CPI provides customers with access to the right experts, equipment, networks, funding opportunities, and more. Frank Millar, CEO, delves into the company\u2019s core purpose and operations.<\/span><\/p>\n

\"Frank
Frank Millar, CEO<\/figcaption><\/figure>\n

\u201cEstablished 20 years ago in the Tees Valley, CPI emerged from the invaluable expertise developed by Imperial Chemical Industries (ICI) in identifying, developing, <\/span>and commercializing new products and processes,\u00a0largely in\u00a0the chemical sector. Even after ICI was broken up and sold, its skills and insights were still recognized as highly valuable by various industries as well as local and regional governments. As a result, business plans were written and proposals were made, leading to the creation of CPI. For the past two decades, our core mission has been to\u00a0assist\u00a0companies in developing proof of concepts, scaling up, and commercializing new products and processes. We work across various sectors, addressing different industry challenges and collaborating with private enterprises, public bodies, and organizations like ours within the UK\u2019s catapult network. Our reach extends into Europe, where we work alongside academia, industry, and government to\u00a0identify\u00a0and exploit market opportunities. However, the conditions necessary to fully realize such market opportunities and successfully commercialize innovations are often not fully met and some intervention is needed,\u201d he begins.<\/span>\u00a0<\/span><\/p>\n

CPI plays a key role in creating the\u00a0optimal\u00a0conditions to achieve these\u00a0objectives, as Frank explains. \u201cThis typically involves a combination of intellectual, financial, and technical resources, which we excel at bringing together. We are an organization of scientists, engineers and business professionals all focused on uniting diverse stakeholders,\u00a0ideas\u00a0and financial and technical instruments to make something innovative happen. More than that, we ensure that this innovation is not only effective but also sustainable, and that it will have a direct and meaningful economic impact. It is this economic impact that drives us. We combine physical, biological, and digital sciences to address industry-recognized challenges,\u00a0anticipating\u00a0the need for transformative solutions. We understand that these changes often require a long-term perspective as it can take years before the effects can be noticed. Therefore, we collaborate to\u00a0establish\u00a0the necessary conditions for industry stakeholders to confidently take a step further along their innovation journey.<\/span>\u00a0<\/span><\/p>\n

\u201cA prime example of our approach and one of our\u00a0best case\u00a0studies is our partnership with Pragmatic Semiconductor (Pragmatic), a company specializing in novel semiconductor processing and products. Over the past 12 years, we have worked closely with them,\u00a0demonstrating\u00a0how the combination of academia, industry, public sector, and private finance interests can lead to significant advancements. I believe that the presence of private finance in this space has become increasingly important in the last few years.\u00a0Arguably, it\u00a0will be the most\u00a0important factor\u00a0in the UK\u2019s capacity to promote its deep tech capabilities. By attracting private finance into this space, we are\u00a0fostering a better understanding of the long-term value and relative risks associated with deep tech innovation,\u201d he adds.<\/span>\u00a0<\/span><\/p>\n

Pragmatic\u2019s long-term collaboration with CPI comes as limitations on the costs and physical properties of traditional, silicon-based circuits are stalling the next wave of innovation. To address this challenge, a revolutionary approach to semiconductor fabrication is essential and enables the creation of a smarter future. By manufacturing integrated circuits that are thinner, more robust, and more affordable, technology can be seamlessly integrated into everyday objects, which unlocks significant benefits. As a global leader in ultra-low-cost flexible electronics, Pragmatic\u00a0leverages\u00a0its flexible integrated circuit technology, known as\u00a0FlexIC, to seamlessly integrate intelligence into a wide range of objects, including packaging and fast-moving consumer goods. This advancement helps deliver the Internet of Things (IoT), allowing organizations to collect, process, and output data throughout an object\u2019s lifecycle.<\/span>\u00a0<\/span><\/p>\n

\"aWith rapid cycle times that\u00a0substantially accelerate\u00a0time to market, Pragmatic\u2019s\u00a0FlexIC\u00a0foundry delivers high-volume fabrication at a fraction of the cost of traditional silicon chips and with a significantly lower environmental impact. CPI\u2019s\u00a0state-of-the-art\u00a0facilities, technical\u00a0expertise, and industrial knowledge have played a key role in accelerating and de-risking Pragmatic\u2019s transition from lab-based proof of concept to commercial fabrication. The partnership has provided extensive support in transforming Pragmatic\u2019s manufacturing process into a scalable model and in developing a resilient production\u00a0methodology.<\/span>\u00a0<\/span><\/p>\n

Beyond Pragmatic, CPI has engaged in many crucial projects. Frank highlights a case study that is particularly important to him. \u201cIn the health and life sciences part of our business, we have been working with RNA, a focus that began before covid and was accelerated through the pandemic. As part of that, we\u00a0established\u00a0an RNA Centre of Excellence\u00a0adjacent to\u00a0our biologics manufacturing facility in Darlington. Recently, we announced\u00a0a really important\u00a0program in collaboration with the UK government and other partners, such as\u00a0Wellcome\u00a0Leap, as part of their global\u00a0Biofoundry\u00a0program. Our Darlington site has been selected as the location for the UK\u00a0Biofoundry, which\u00a0greatly enhances\u00a0the capabilities that we have in that facility. This innovative manufacturing technology program aims to bring continuous manufacturing skills and approaches into the production of RNA therapies.<\/span>\u00a0<\/span><\/p>\n

\u201cThe health services and life sciences sectors are eager to explore RNA therapies for a broader range of diseases and conditions, including cancer, dementia, and other chronic diseases that are hard to treat. RNA therapies\u00a0represent\u00a0a promising area of medicine, and our ability to produce material for clinical trials in such an agile manner is crucial. As we often work with small patient groups, we only need to produce\u00a0relatively modest\u00a0amounts of material for trials. The agility provided by the\u00a0Biofoundry\u00a0model and its technology will give the UK a globally significant position in supporting innovative and\u00a0cutting-edge\u00a0RNA therapies.\u201d<\/span>\u00a0<\/span><\/p>\n

In June 2025, CPI opened a new Advanced Materials Battery Industrialisation Centre (AMBIC) in County Durham, a facility designed to accelerate the development of breakthrough battery materials. \u201cAMBIC\u00a0represents\u00a0a very strong\u00a0collaboration stemming from the\u00a0previous\u00a0industrial strategy, not the one the government has just launched, but the prior initiative that created the Faraday Battery Challenge. We partnered effectively with colleagues like the Warwick Manufacturing Group and discovered complementary capabilities in energy storage materials and the\u00a0development of battery technology. This collaboration\u00a0facilitates\u00a0the transition from prototyping to small-scale manufacturing, which linked nicely with the UK Battery Industrialisation Centre. Through the Faraday Battery Challenge, we have managed to form a kind of supply chain that encompasses everything from fundamental chemistry to the final product.<\/span>\u00a0<\/span><\/p>\n

\u201cAMBIC is a good example of an intervention, as I mentioned earlier, since it\u00a0provides\u00a0a physical capability within the supply chain while recognizing the importance of future chemistries, robotics, and automation. When we make a good case for building specifically targeted and designed infrastructure, we can improve the strength and resilience of that supply chain, thereby increasing the innovation potential it offers to industry. Programs like AMBIC can achieve this by deeply reinforcing the partnerships\u00a0established\u00a0among collaborators with existing facilities. These partners have recognized that if we had infrastructure like AMBIC, we could significantly accelerate and deepen our innovation offerings within the supply chain,\u201d Frank elaborates.<\/span>\u00a0<\/span><\/p>\n

In September, CPI announced its intention to form a joint venture with Quotient Sciences (Quotient), a leader in developing and delivering clinical trials. \u201cOur goal is to join up our RNA manufacturing capability with Quotient\u2019s design and delivery of clinical trials so that we can bring these therapies to market safely and with agility. For many years, we have focused on engineering biology, one of the five key technology areas that the government wants the UK to lead. We have applied engineering biology in both industrial and health contexts. In Teesside, we have an advanced industrial biotechnology capability that\u00a0showcases\u00a0the power and benefits of engineering biology. We are committed to creating a modern industrial bioeconomy, and this work is ongoing. To that end, we are collaborating with a strong network of partners in the Northeast, including\u00a0Therascience, York University,\u00a0BioYorkshire, the\u00a0North East\u00a0of England Process Industry Cluster, the York and North Yorkshire Mayoral Authorities, our combined authority, and the Tees Valley Combined Authority. The shift toward producing pharmaceutical materials through biomanufacturing\u00a0represents\u00a0a\u00a0significant change\u00a0in how we manufacture chemicals and materials, moving away from fossil fuels. This presents an exciting opportunity within a modern industrial bioeconomy, which is crucial for global sustainability,\u201d Frank ends.\u00a0<\/span>\u00a0<\/span><\/p>\n

www.uk-cpi.com<\/span>\u00a0<\/span><\/a><\/p>\n","protected":false},"excerpt":{"rendered":"

As a leading independent technology innovation\u00a0center\u00a0and a founding member of the UK Government\u2019s High Value Manufacturing Catapult, CPI applies its<\/p>\n","protected":false},"author":6,"featured_media":56313,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"content-type":"","footnotes":""},"categories":[685,657],"tags":[4065,4066,1801,4034],"class_list":["post-56312","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-technology","category-insights","tag-cpi","tag-rna-therapoes","tag-semiconductors","tag-4034"],"acf":[],"yoast_head":"\nFrom RNA therapies to smart semiconductors, CPI transforms the UK\u2019s brightest ideas into market-ready solutions\u00a0<\/title>\n<meta name=\"description\" content=\"As a leading independent technology innovation\u00a0center\u00a0and a founding member of the UK Government\u2019s High Value Manufacturing Catapult\" 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